In 1962, as Uganda approached independence, a historical account noted that Karamoja was seen as an ‘oddity’ and faced poor relations with the rest of the nation. This observation highlights the region’s marginalization even as colonial rule ended. Dr. Ayub Mukisa argues that while the colonial era is over, the people of Karamoja continue to suffer from neglect and underdevelopment. The transition from colonial administration to local governance was meant to empower the Karamoja community, but historical records show that this promise has not been fulfilled. Despite years of colonial rule, the region remains marginalized, with little progress in improving living conditions or infrastructure. Mukisa emphasizes that his tears are not for the colonial past but for the ongoing struggles of the Karamoja people who have been left behind. This sentiment underscores a deeper issue of systemic neglect and inequality that persists long after independence. The article calls for greater attention to the needs and rights of the Karamoja community, highlighting their continued marginalization in post-colonial Uganda.